6-氨基-1,3-二甲基尿嘧啶6-Amino-1,3-dimethyluracil(DMAU)
用途Application:
6-氨基-1,3-二甲基尿嘧啶(6-氨基-1,3-二甲基脲嘧啶),用于API的合成,也廣泛用于PVC熱穩(wěn)定劑的原輔料;
6-Amino-1,3-dimethyluracil(DMAU),?in?pharmaceutical?industry,?use?it?in?synthesis?of?Theophylline?and?etc.;?also?can?be
?widely?used?as?ingredient?for?PVC?heat?stabilizer;
簡介Capacity:
該產(chǎn)品是我公司的主打產(chǎn)品之一,我公司為該產(chǎn)品大生產(chǎn)商,有歐盟REACH正式注冊;It?is?our?strong?product,?we?are?the?leading?manufacturer?of?it,?have?formal
EU-REACH?registration;
?
技術(shù)說明書Technical?Data?Sheet:
化學(xué)名:6-氨基-1,3-二甲基尿嘧啶(6-氨基-1,3-二甲基脲嘧啶)
Chemical?Name:?6-Amino-1,3-dimethyluracil(DMAU)
分子式Formula:?C6H9N3O2
分子量MW:?155.16
Cas#:?6642-31-5
結(jié)構(gòu)式Structure?Formula:
物理特性Physical?Properties:
顏色Color:?類白色到淡黃色粉末off-white?to?light?yellow?powder;
20degC下比重Specific?Gravity?at?20degC:?無N/A;
規(guī)格Specifications:
含量Assay:?大于99.0%?min.;
干燥失重loss?on?drying:?小于1%max.;
粒度Particle?size,?45μm:?大于99%min.;
包裝Packing:
25kgs塑編袋25kgs?plastic?woven?bag;
產(chǎn)品作用原理mechanism:
一、6-氨基-1,3-二甲基尿嘧啶(簡稱DMAU)作用原理:
熔點(diǎn)高達(dá)290℃以上,200℃加熱減量<1%,本身特性能夠適應(yīng)PVC生產(chǎn)過程。?DMAU能吸收PVC生產(chǎn)
過程中產(chǎn)生的HCl,還能取代不穩(wěn)定的Cl原子。與ZnSt2共同使用時(shí),?DMAU能與ZnCl2發(fā)生反應(yīng),生成
金屬絡(luò)合物,使ZnCl2失去活性,能防止“鋅燒”,大大增強(qiáng)
PVC樣品的長期穩(wěn)定性;DMAU中主要基團(tuán)尿嘧啶是人體必需的四種核苷酸之一,對人體安全無害;
DMAU因此被認(rèn)為是高效且安全的熱穩(wěn)定劑;
A.?Mechanism:
with?melting?point?of?more?than?290degC,?loss?on?drying?under?200degC?of?less?than?1%,?it?suits?for?
PVC’s?producing?process.?Can?absorb?HCl?which?is?by-produced?during?producing?process?of?PVC,?can?replace?Cl-?which?is?not?stable.?When?be?used?with?
ZnSt2,?can?react?with?ZnCl2?to?create?metal?complex,?then?ZnCl2?losses?its?activity,?so?can?avoid?PVC’s?
color?from?changing?into?darker,?improve?PVC’s?long?term?stability;?Its?basic?chemical?structure?‘uracil’?is
?one?of?the?essential?nucleotides?of?the?human?body,?has?no?hazardous?to?human;?So?it?is?taken?as?PVC
?heat?stabilizer?of?high-efficiency?and?safety;
二、DMAU與ZnSt2:
含有DMAU/ZnSt2復(fù)合穩(wěn)定劑,無論初期白度還是長期穩(wěn)定性都比含有CaSt2/ZnSt2復(fù)合穩(wěn)定劑的更好。
DMAU與ZnSt2共同使用時(shí)具有良好的系統(tǒng)穩(wěn)定效果,比目前工業(yè)上常用的的協(xié)同效果更好;
B.?DMAU?and?ZnSt2:
Stabilizer?of?DMAU/ZnSt2?is?better?than?stabilizer?of?CaSt2/ZnSt2?on?both?initial?whiteness?and?long?term?
stability;?DMAU/ZnSt2?is?of?systematic?stability,?its?efficiency?is?better?than?that?of?CaSt2/ZnSt2,?which?is?
of?synergistic?stability;
三、?DMAU與水滑石(或沸石):
DMAU與水滑石(或沸石,沸石更節(jié)省成本)同時(shí)使用,在鈣鋅穩(wěn)定劑的配方中,加入3-4%的DMAU和
8-10%的水滑石或沸石,能更好地抑制PVC初期著色度,該配方更加經(jīng)濟(jì)可靠;
C.?DMAU?and?Hydrotalcite(or?Aluminosilicate):
To?add?3-4%?of?DMAU?and?8-10%?hydrotalcite(or?Aluminosilicate,?whose?cost?is?lower)?into?Calcium/Zinc?stabilizer,?it?can?improve?
PVC’s?initial?colorless,?and?is?more?economic;
四、DMAU與β-二酮:
DMAU與β-二酮都是新興的有機(jī)穩(wěn)定劑,兩者單獨(dú)進(jìn)行比較,DMAU在抑制初期著色和長期熱穩(wěn)定性
方面都能更勝一籌。實(shí)際生產(chǎn)過程中DMAU既可以完全替代β-二酮,也可以與β-二酮共同使用;
D.?DMAU?and?Stearoyl?benzoyl?methane:
DMAU?can?improve?PVC’s?initial?colorless?and?long?term?heat?stability,?so?is?Stearoyl?benzoyl?methane;
?when?preparing?PVC?stabilizer,?DMAU?can?replace?stearoyl?benzoyl?methane,?DMAU?can?be?used?together
?with?stearoyl?benzoyl?methane?also;
五、DMAU發(fā)展歷程:
DMAU應(yīng)用于PVC穩(wěn)定劑的技術(shù)早是由美國Chemtura研發(fā),其將DMAU廣泛的應(yīng)用于其各種無鉛穩(wěn)定劑的
配方中。隨著對鉛鹽穩(wěn)定劑的限制,DMAU作為無鉛穩(wěn)定劑中的新星。新華制藥是國內(nèi)外大的
DMAU生產(chǎn)商。
E.?History?of?DMAU:
The?world?main?producers?of?PVC?stabilizer?are?cooperating?with?us.?Accompany?more?and?more?countries?
forbid?to?use?lead?salts?PVC?stabilizer,?it?will?be?used?more?and?more?widely;?We?are?the?leading?
manufacturer?of?DMAU.?